Blog articles

Review of the book "Laborstatistik für technische Assistenten und Studierende " (Laboratory statistics for technical assistants and students)

Written by Dr. Janet Thode on . Posted in Think out of the box

In the meantime, I’ve read - still enthusiastically - another "essentials" booklet by Patric U.B. Vogel. In today's post, I’d like to introduce the book "Laboratory Statistics for Technical Assistants and Students" (2021 published by Springer Spektrum, Wiesbaden; ISBN: 978-3-658-33206-8) and provide my personal feedback.

Write comment (0 Comments)

New potency assays for anti-VEGF antibodies

Written by Dr. Janet Thode on . Posted in Method validation

Introduction and Background

The group of vascular endothelial growth factors (VEGF) plays a crucial role in the formation of new blood vessels (angiogenesis), since they stimulate the growth, i.e. the division and migration of endothelial cells, as the name already suggests. Since some tumor types can better supply themselves with nutrients via increased angiogenesis and thus grow faster, anti-VEGF antibodies represent significant cancer therapeutics. However, the various types of cancer are not the only indication; enhanced angiogenesis is also important in certain eye diseases.

Anti-VEGF antibodies or fragments include bevacizumab (Avastin®), ranibizumab (Lucentis®) or aflibercept (Eylea®) and an increasing number of biosimilars already on the market and in late-stage clinical trials, such as Mvasi®, Zirabev® or BevaciRel®.

Write comment (0 Comments)

Review of the book "Trending in der pharmazeutischen Industrie" (Trending in the pharmaceutical industry)

Written by Dr. Janet Thode on . Posted in Think out of the box

And we continue reviewing pharmaceutical "essentials" books. With unbroken enthusiasm, I jumped at the book "Trending in the pharmaceutical industry" by Patric U.B. Vogel this time, published in 2020 by Springer Spektrum, Wiesbaden (ISBN: 978-3-658-32206-9) and spent a cozy evening in front of the chimney.

Write comment (0 Comments)

Journal Club: Validation of Raman spectroscopy for content determination in tablets

Written by Dr. Janet Thode on . Posted in Method validation

The various techniques of Raman spectroscopy find a wide range of applications in the different areas of the pharmaceutical industry, be it for the detection of counterfeits, as an in-process control (IPC) during the production of the active pharmaceutical ingredient, for content determinations, as an ID test for vaccines, for the simultaneous determination of several product quality attributes (PQAs) as part of a rapid release strategy, up to sterility tests, to name just a few examples [1-4].

Write comment (0 Comments)

Review of the book "Qualitätskontrolle von Impfstoffen” (Quality control of vaccines)

Written by Dr. Janet Thode on . Posted in Think out of the box

After outing myself in the last blog article as a fan of the "essentials" series, I’ve enthusiastically read some more books, but unfortunately haven’t found any time for reviews yet. This should change right now. Therefore, in this blog article I’d like to present the book "Quality Control of Vaccines" by Patric U.B. Vogel, published in 2020 by Springer Spektrum, Wiesbaden (ISBN: 978-3-658-31864-2). Of course, this book has also accompanied me - in keeping with tradition - on a vacation 😉

Write comment (0 Comments)

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.